Colgate at Syracuse Prediction & Betting Pick | College Football Week 3
📅 Date: Friday, September 12, 2025
🕖 Time: 7:00 PM EST
🏟️ Venue: JMA Wireless Dome – Syracuse, NY
Game Preview
The Syracuse Orange return home for a non-conference matchup against the Colgate Raiders in Week 3. Syracuse enters at 1-1, looking to build momentum after a dramatic overtime win over UConn, while Colgate sits at 0-2 following narrow losses to Monmouth and Villanova.
Fran Brown has emphasized culture and accountability in his first season at Syracuse. After a sluggish performance against UConn, Brown even had his players run postgame sprints in front of fans, demanding sharper execution moving forward. Quarterback Steve Angeli impressed with 417 passing yards and two touchdowns in that game, while receiver Justus Ross-Simmons continues to emerge as a reliable playmaker.
For Colgate, first-year head coach Curt Fitzpatrick has his team playing hard despite the slow start. Quarterback Zach Osborne threw for 239 yards last week, with Treyvhon Sanders hauling in 10 receptions for 137 yards and a touchdown. Still, competing at the FBS level—especially against Syracuse’s defensive front—will be a tall order.
Key Matchup Notes
Syracuse is 22-0 all-time against FCS opponents since the 1978 division split.
The Orange have won 17 straight meetings against Colgate.
Colgate has averaged 28 points per game this season but has also given up over 33 points per game defensively.
Syracuse has shown a tendency to control tempo at home, particularly in non-conference matchups.
Betting Outlook
Syracuse should win this game comfortably, but the spread may be less reliable given the possibility of second-half substitutions once the outcome is decided. The more stable angle lies in the total. The Orange defense should limit Colgate’s scoring chances, while Syracuse may lean on its run game and chew clock once ahead.
With the line inflated due to Syracuse’s offensive explosion potential, value leans toward the under. Expect Syracuse to jump out early, then slow things down as they cruise to a routine victory.
📌 Official Pick
Under 66.5 (-110)
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