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Ohio State at Indiana Prediction & Betting Pick | College Football October 17, 2026
This feels like the perfect setup for another Jeremiah Smith takeover game. The Ohio State star has a massive 35% target share, averages 8 catches per game, and tends to save his biggest performances for matchups where the Buckeyes actually need all four quarters from their starters. That's exactly what this Top-10 showdown against unbeaten Indiana projects to be. Smith already burned the Hoosiers for 144 yards in last year's Big Ten Championship Game, and this version of Indiana's secondary isn't as talented as the one he faced then. With national attention on Ohio State's toughest stretch of the season and a competitive game script likely keeping the passing attack aggressive throughout, the volume and ceiling are both there for another monster outing.