Monday night sets up perfectly for Puka Nacua in what could be one of the best receiver matchups of the week. Buffalo's secondary has struggled to contain opposing WR1s, allowing big performances to players like Amon-Ra St. Brown, and the Bills continue to rank near the bottom of the league against outside receivers. That's exactly where Nacua does most of his damage. He's averaging 99.5 receiving yards per game, owns a 26% target share when healthy, and is coming off a 125-yard explosion against Philadelphia. With Matthew Stafford expected to lean heavily on his top weapon against a defense that plays plenty of zone coverage, this is a spot where Nacua can once again be the focal point of the Rams' offense while Los Angeles defends home turf in a potential shootout.