Cleveland Browns at Detroit Lions Prediction & Betting Pick | NFL 25-26 Week 4
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Date: Sunday, September 28, 2025
๐ Time: 1:00 PM EST
๐๏ธ Venue: Ford Field - Detroit, MI
The Detroit Lions enter Week 5 looking to continue their strong offensive rhythm inside Ford Field, and one of the biggest emerging storylines has been the development of Jameson Williams. While Amon-Ra St. Brown remains the unquestioned WR1 and Jared Goffโs most trusted target, Williams has provided the element this offense has been craving: a consistent vertical deep-ball threat.
Williams comes into this matchup averaging a ridiculous 21.8 yards per reception, which ranks among the league leaders. That kind of efficiency shows he doesnโt need high volume to cash a receiving yard prop like this โ he can clear it in just two or three receptions. His speed forces defenses to respect the deep ball, and when they donโt, he can flip the field in a single play.
The Brownsโ defense has been stingy this season against short-to-intermediate passing routes, but theyโve been more vulnerable when offenses stretch the field vertically. With so much attention required to slow down St. Brown and the Lionsโ run game, Cleveland is going to be forced into single coverage scenarios against Williams at times โ a dangerous gamble considering his explosiveness.
What makes this prop appealing is that the Lions are scheming ways to get him more involved. Even if he only sees four or five targets, the efficiency and explosive nature of those looks give him a high ceiling. Heโs also due for some touchdown regression โ with only one score despite his usage, thereโs clear potential for him to hit paydirt soon.
This sets up perfectly for Williams to go over his modest receiving yard number. At 43.5 yards, we donโt need a monster performance โ one or two chunk plays could easily get us across the line.
๐ Official Pick
Jameson Williams (Detroit Lions) Over 43.5 Receiving Yards -112
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