Iowa State at Oklahoma State Prediction & Betting Pick | College Football Saturday November 29, 2025
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Date: Saturday, November 29, 2025
๐ Time: 12:00 NN EST
๐๏ธ Venue: Boone Pickens Stadium - Stillwater, OK
Iowa State heads into Stillwater riding momentum. The Cyclones have stacked back-to-back wins, including a dominant 24-point victory over Kansas, and now sit at 7โ4 with a chance to close the regular season strong. Oklahoma State, meanwhile, is limping to the finish line at 1โ10, fresh off yet another loss โ this time by three at UCF.
The Cyclonesโ offense has been steady all year. Rocco Becht has thrown for 2,471 yards and 15 touchdowns, spreading the ball around with confidence. Carson Hansen leads the ground game with 841 yards and six scores, while Abu Sama III adds another 645 rushing yards. Brett Eskiidsen has been the top target in the passing game, averaging big plays with five touchdowns on just 29 catches. This group has balance, and that makes them tough to scheme against.
Oklahoma Stateโs offense, on the other hand, has struggled to find rhythm. Zane Flores has just three touchdown passes all season, and the run game hasnโt been enough to compensate. Rodney Fields Jr. leads with 614 yards but only one score, while Gavin Freeman is the lone bright spot in the passing attack with 435 yards and four touchdowns. Itโs been a grind for this unit, and facing Iowa Stateโs defense doesnโt make things easier.
Matchups like this usually come down to whether the underdog can hang around early. But Oklahoma State has shown no ability to sustain drives or finish games. Iowa Stateโs defense has been opportunistic, and against a freshman quarterback with limited weapons, the Cyclones should control the tempo from the start.
The line sits at -14, and Iโm comfortable laying it. Iowa State has the firepower to build a cushion quickly, and Oklahoma State simply doesnโt have the offense to trade scores. With the Cyclones riding confidence and the Cowboys stuck in a spiral, this feels like a one-sided affair.
Expect the Cyclones to dictate the pace, pull away early, and cover with ease on the road.
๐ Official Picks
Iowa State -14 -110
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